Self-Assembling Amphiphilic Systems (Phase Transitions and Critical Phenomena)

by C. Domb

Publisher: Academic Press

Written in English
Cover of: Self-Assembling Amphiphilic Systems (Phase Transitions and Critical Phenomena) | C. Domb
Published: Pages: 208 Downloads: 702
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Edition Notes

ContributionsMichael Schick (Editor)
The Physical Object
Number of Pages208
ID Numbers
Open LibraryOL7326524M
ISBN 10012220316X
ISBN 109780122203169

It is crucial for hydrophobic drugs to be dissolved and stabilized by carriers in aqueous systems and then to be delivered into target cells. An amphiphilic self-assembling peptide EAKI (Ac-AEAKAEAKAEAKAEAK-NH2) is reported here to be able to stabilize a model hydrophobic compound, pyrene, in aqueous solution, resulting in the formation of colloidal by: 5. Dynamics of Surfactant Self-Assemblies offers a unique and comprehensive review of the literature that exists on the dynamics of the various surfactant self-assemblies and a unified perspective on this topic. It provides researchers with a useful guide for the dynamics of the surfactant systems that they wish to investigate. The role of hydrogen bonding and amphiphilic packing in the self-assembly of peptide−amphiphiles (PAs) was investigated using a series of 26 PA derivatives, including 19 N-methylated variants and 7 alanine mutants. These were studied by circular dichroism spectroscopy, a variety of Fourier transform infrared spectroscopies, rheology, and vitreous ice cryo-transmission electron microscopy. Large, hydrophilic polyoxoanions with high solubility in water and/or other polar solvents demonstrate unique solution behavior by self-assembling into single layer, hollow, spherical “blackberry” structures, which is obviously different from small, simple ions. These macroions cannot be treated as insoluble colloidal suspensions because they form stable “real solutions”.

Self-assembling amphiphilic lipids or polymers have been successfully used in pharmacotherapy as drug solvents or carriers, improving the bioavailability of water-insoluble drugs. This review focuses on an unusual hypersensitivity reaction (HSR) caused by a micellar (Cremophor EL, CrEL) and a monomeric block copolymer (poloxamer Cited by: We report an extensive simulation study on the spontaneous formation of complex micelles from coil-rod-coil amphiphilic triblock copolymers in dilute solution resulting from solvent selectivity. The amphiphilic molecule is built from one hydrophilic block on each side and a hydrophobic block in the middle. TCited by: Pennsylvania for postdoctoral studies towards self-assembling amphiphilic dendrons (with Dr. Virgil Percec, Department of Chemistry), amphiphilic polymers and their supra-molecular assemblies as drug delivery systems in cancer pharmacology (with Drs. Vladimir Muzykantov and Ian Blair, Department of Pharmacology). In he.

Self-Assembling Amphiphilic Systems (Phase Transitions and Critical Phenomena) by C. Domb Download PDF EPUB FB2

Self-Assembling Amphiphilic Systems, Volume 16 | Gerhard Gompper, M. Schick, Cyril Domb, Joel L. Lebowitz | download | B–OK. Download books for free. Find books. This book describes that progress by focusing on three principal approaches to self-assembling amphiphilic systems; that of microscopic models, of intermediate length scale Ginzburg-Landau models, and of the largest length scale interfacial, or membrane, models.

At the same time, the theoretical description of these systems has made considerable progress. This book describes that progress by focusing on three principle approaches to self-assembling amphiphilic systems: microscopic models; intermediate length scale Ginzburg-Landau models; and large length scale interfacial (or membrane) models.

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The self-assembly of several classes of amphiphilic peptides is reviewed, and selected applications are discussed.

We discuss recent work on the self-assembly of lipopeptides, surfactant-like peptides and amyloid peptides derived from the amyloid-β influence of environmental variables such as pH and temperature on aggregate nanostructure is by: Provides comprehensive knowledge on concepts, theoretical methods and state-of-the-art computational techniques for the simulation of self-assembling systems Looks at the field of self-assembly from a theoretical perspective Highlights the importance of theoretical studies and tailored computer simulations to support the design of new self-assembling materials with useful properties Divided.

Amphiphiles are synthetic or natural molecules with the ability to self-assemble into a wide variety of structures including micelles, vesicles, nanotubes, nanofibers, and lamellae.

Self-assembly processes of amphiphiles have been widely used to mimic biological systems, such as assembly of lipids and proteins, while their integrated actions allow the performance of highly specific cellular Cited by: Lipid-like amphiphiles have been used in several self-assembling nanoparticulate-based self-adjuvanting antigen delivery systems because their structure mimics bacterial lipoproteins and as such can activate the immune system.

90 This type of vaccine formulation includes a hydrophobic core covalently attached to a hydrophilic peptide antigen. download self-assembling amphiphilic systems the book by organising it into the story.

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1 Theoretical Studies and Tailored Computer Simulations in Self-Assembling Systems: A General Aspect 1 Zihan Huang and Li-Tang Yan. Introduction 1. Emerging Self-Assembling Principles 3. Predictive Science and Rational Design of Complex Building Blocks 3.

Entropy-Driven Ordering and Self-Assembly 5. Programmable Self. This option allows users to search by Publication, Volume and Page Selecting this option will search the current publication in context.

Selecting this option will search all publications across the Scitation platform Selecting this option will search all publications for the Publisher/Society in contextCited by: Amphiphilic derivatives were designed to improve the cell targeting of the drug-containing cyclodextrin cavities through their transportation in the organism, within self-assembling systems.

Amphiphilic cyclodextrins can self-assemble into water-soluble aggregates such as mono or polydisperse micelles, or insert in lipid membranes and by: Mesoscale simulations (see Figure S1, Table S1, and text in Supporting Information for details) were initially employed to predict the self-assembly of all dendrons 1–ing to the in silico results, the amphiphilic dendrons 1–6 were able to auto-organize into spherical nanosized micelles (shown in Figure 1 for dendrons 4, 3 and 2 as an example), with an average diameter D and Cited by: 4.

Amphiphilic azo polymers with different functional groups and chain structures show wealthy self-assembling behavior. Over the past decades, self-assembly of amphiphilic azo polymers has been broadly investigated to obtain functional ultrathin films, supermolecular aggregates, colloidal arrays, and phase-separation films among others.

Cited by: The self‐assembly of several classes of amphiphilic peptides is reviewed, and selected applications are discussed. We discuss recent work on the self‐assembly of lipopeptides,Cited by: Schwarz U., Gompper G. () Bicontinuous Surfaces in Self-assembling Amphiphilic Systems.

In: Mecke K., Stoyan D. (eds) Morphology of Condensed Matter. Lecture Notes in Physics, vol Cited by: The physics of soft condensed matter is probably one of the most 'fashionable' areas in the physical sciences today. This book offers a coherent and clear introduction to the properties and behaviour of soft matter.

It begins with a treatment of the general underlying principles: the relation of the structure and dynamics of solids and liquids to intermolecular forces, the thermodynamics and. The self-assembly processes of amphiphilic molecules in solution have been actively studied during the past decades.

Although reports on the experimental and theoretical studies are abundant in. The book first discusses self-assembling processes taking place in aqueous surfactant solutions and the dynamic character of surfactant self-assemblies.

The next chapter reviews methods that permit the study of the dynamics of : Hardcover. Self-Assembling Peptide Systems in Biology, Medicine and Engineering / Edition 1.

(Alzheimer's) diseases. This is a pointer to the wider significance of the self-assembling properties of polypeptides. It has been long known that, in silk, polypeptides are assembled into- sheet structures which impart on the material its highly exploitable Brand: A.

Aggeli. Bicontinuous surfaces in self-assembling amphiphilic systems. In D. Stoyan (Ed.), Morphology of condensed matter: physics and geometry of spatially complex Cited by: Peptide amphiphiles are peptide-based molecules that self-assemble into structures including high aspect ratio nanofibers.

A peptide amphiphile typically comprises a hydrophilic peptide sequence with an attached lipid chains, in this case being a lipopeptide. They were first described by the group of Matthew Tirrell in These molecules are often composed of multiple domains which allow.

The main focus of the book is the design, synthesis and characterization of amphiphile self-assemblies and the dynamic assessment of these assemblies as delivery systems for drugs and nucleic acids.

Control of Amphiphile Self-Assembling at the Molecular Level - Marc A. Ilies - Oxford University Press. Request PDF | Self-Assembling Peptide Systems in Biology, Medicine and Engineering | Foreword.

Exploiting peptide self-assembly to engineer novel biopolymers: tapes, ribbons, fibrils and fibres. A novel type of self-assembling peptides has been developed by introducing the basic elastomeric β-turn units of elastin protein into the amphiphilic peptide molecules.

The self-assembly behaviors of such peptides are affected by the overall molecular hydrophobicity, charge distribution and temperature. The molecules with higher hydrophobicity exhibit better self-assembling capability to form. The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d-lactose in their hydrophilic part is reported.

These unprecedented sugar-containing dendrimers are named amphiphilic Janus glycodendrimers. Their self-assembly by simple injection of THF or ethanol solution into water or Cited by: U.

Schwarz and G. Gompper, Bicontinuous surfaces in self-assembling amphiphilic systems, In: Morphology of Condensed Matter: Physics and Geometry of Spatially Complex Systems, Eds. Mecke and D.

Stoyan, Springer Lecture Notes in Physics Vol. pp. (abstract, cond-mat/, PDF, the complete volume at Springer). Accurate calculation of functions used in a model of the nematic behavior of self-assembling systems.

Author: Alan E. Berger Journal: Math. Comp. 54 F. Hildebrand, Introduction to numerical analysis, McGraw-Hill Book Company, Inc., New York-Toronto-London, Theory of liquid crystalline phases in amphiphilic systems, Molecular. Amphiphilic conjugated thiophenes for self-assembling antenna systems in water (journal articles, books or book chapters) do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

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Self-Assembling Amphiphilic Systems Dr. Helge Klemmer Physical Chemistry, University of Cologne, D Köln, Germany Funktionen & Anwendungen Sommersemester University of Cologne Low surfactant content, low energy input: emulsions (usually micrometer size, very instable).Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience Silvia Cavalli,*ab Fernando Albericio*abc and Alexander Kros*d Received 8th July First published as an Advance Article on the web 13th October   Natural pore-forming proteins act as viral helical coats1 and transmembrane channels2,3,4, exhibit antibacterial activity5 and are used in synthetic systems, such as for reversible encapsulation6.